With the foreign analogues


In the chart we include information about cryosurgical equipment with automatic control and indication system and also providing the temperature of cryoexposure no more than minus 140°C.

Parameter “Cryo-Pulse” Ukraine German analogue American and Israeli analogues
1 Cryoexposure temperature range, °С 0 — minus 180 (in contact with freezing tissue) No info in advertisement 0 — minus 160 (design chart, real temperature isn’t measured)
2 Applied cryogen Liquid nitrogen Liquid nitrogen Gaseous argon
3 Freezing zone volume 5-180 cm3 Diameter 25 mm No info in advertisement
4 Time for emergency warming, minute 2,0 No info in advertisement No info in advertisement
5 Accuracy of temperature stabilization under cryo-exposure, °С ± 5 No info in advertisement No info in advertisement
6 Time required to be ready for use, minute No more than 2 2-3 1
7 Time of continuous operation under condition of one filling of cryostat, minute No less than 120 (9 liters of cryogen) 30 (47 liters of cryogen) No info in advertisement
8 Consumed power, W 600 No info in advertisement 700
9 Working pressure, atm 2.5 15 50
10 Size, mm 400х600х1400 550х550х1300 483×635x1245
11 Weight, kg 85 90 52,6
12 Quantity of cryo-instruments and applicators 3+16 6 8
13 Fields of application Abdominal oncology, gynecology, proctology, dermatology, tumor of mammary gland, urology. With necessary cryo-instruments it can be applied in any medicine field Urology, liver tumors Urology, liver tumors
14 Requirements to personnel Average level Technical personnel with special training No info in advertisement
  • Cryoexposure temperature range. The important factor is the minimum temperature, which can provide the efficiency for cryomethod application. It should reach no more than minus 180°C in contact of applying surface of cryoinstrument or applicator with freezing tissue.The “Cryo-Pulse” technology reaches this parameter through heat exchange in heat exchange chamber, where one or several surfaces are the working surfaces of cryoinstruments and applicators. Weak structure and parameters of the chamber provide nucleate boiling regime of liquid nitrogen and maximum heat exchange coefficient (intensive heat exchange).In German cryosurgical devices pumps liquid nitrogen through heat exchange chamber in order to reduce the steady-state film boiling regime with new portion of cryogen (extensive heat exchange). Besides liquid nitrogen is pumped under the pressure of 15 atm. It means that its boiling temperature increases up to minus 175°C. In such a model the minimum real temperature of cryoexposure is minus 140°C.In American and Israeli uses gaseous argon as a cryogen. Under high-pressure it goes to heat exchange chamber and while expanding (Joule-Thompson effect) is cooled up to minus 140°C. Under these conditions the gas is not liquefying. Real temperature of working surface of cryoinstruments is not measured, but with high probability one can assure that in contact with freezing tissue temperature can’t fall down lower than minus 80-100°C.
  • Applied cryogen.
    • Liquid nitrogen is the most preferable cryogen for application in cryosurgical equipment. It possesses the highest specific heat of evaporation and sufficiently low boiling temperature; it is available, nontoxic and inexpensive.
    • The application of gaseous argon reduces the efficiency of cryoexposure because heat capacity of liquid cryogen some times higher than gaseous under the same temperature. It means that heat abstraction in the equipment with liquid gases is much higher.
  • Freezing zone. Freezing zone completely depends on real temperature of working surface of cryoinstrument or applicator and on the square of this surface.
  • Time of emergency warming. In cryoexposure the working surface of cryoinstrument “sticks” to the freezing tissue. So in order to detach it after cryooperation, it is necessary to warm the working part up to plus temperature. Our model performs it by pumping preheated gaseous cryogen. Foreign analogues perform warming spontaneously — near 10-15 minutes. It prolongs the operation time and causes inconvenience.
  • Accuracy of measuring and stabilization of cryoexposure temperature is a very important parameter of cryosurgical equipment. In “Cryo-Pulse” we have miniature low temperature sensor built into the working surface of every cryoinstrument or applicator. It provides accuracy of measuring real temperature of cryoexposure. High accuracy of stabilization of cryoexposure temperature is provided with switching on/off electromagnetic valve, placed in immediate vicinity from heat exchange chamber. In devices which produced in German temperature is presumably measured by thermocouple in flow of liquid nitrogen, which checks its boiling temperature.In other producers devices temperature is not measured.
  • Time required to be ready for use. It is not correct to compare time required to reach minimum temperature as every equipment deals with minimum temperature of different subjects:
    • “Cryo-Pulse” — working surface of cryoinstrument or applicator;
    • in German apparatus — flow of liquid cryogen;
    • in American and Israeli — no measuring devices.
  • Time of continuous work from one filling. Time of continuous work from one filling is determined by quality of heat exchange.
    • “Cryo-Pulse” — intensification of heat exchange allows using effectively latent heat of vaporization of liquid nitrogen and providing continuous work during minimum 120 minutes under condition of using applicators with large working surface;
    • the best German analogues — as the result of extensive heat exchange 47 liters of liquid nitrogen is pumped through 6 cryoinstruments with diameter 3.2 mm during 30 minutes (1.5 ltr/min).
  • Consumed power. In “Cryo-Pulse” consumed power can be reduced by 15-20%.
  • Working pressure. In “Cryo-Pulse” maximum working pressure of 2.5 atm is determined by construction of heat exchange chambers, which allows intensifying heat exchange process and using liquid nitrogen with high output.In German device working pressure of 15 atm is also determined by the construction of heat exchange chambers, which does not allow intensifying heat exchange process, which is based on intensive pumping of large quantity of liquid cryogen.
  • Field of application. With quick detachable docking assemblies in “Cryo-Pulse” as cryoprobe-cryoinstrument and cryoinstrument-applicator it is possible to use limitless quantity of cryoinstruments and applicators, i.e. unit “Cryo-Pulse” is multi-purpose and can be applied in practice in all medicine fields.
  • Requirements to personnel. Unit “Cryo-Pulse” is simple, reliable, safe in operation, its service is realized by average medical personnel.Exploitation of unit foreign producers is carried out by technical personnel with special knowledge on cryogenic systems.
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